NB.1.8.1 Variant Detected in U.S. and India

Overview

A new COVID-19 variant, NB.1.8.1, has been identified in multiple countries, including the United States and India. This variant, a sublineage of the Omicron JN.1 strain, is currently under monitoring by global health authorities due to its potential for increased transmissibility. (The Times of India)

Global Detection and Spread

United States

The Centers for Disease Control and Prevention (CDC) has detected NB.1.8.1 cases through airport screening programs in California, Washington, Virginia, and New York. Additional cases have been reported in Ohio, Rhode Island, and Hawaii. These detections primarily involve international travelers from countries such as China, Japan, South Korea, and France. (Economic Times, Daijiworld, NDTV)

India

India has reported one case of NB.1.8.1 in Tamil Nadu and four cases of a related variant, LF.7, in Gujarat. Both variants are being closely monitored by the Indian SARS-CoV-2 Genomics Consortium (INSACOG) and the World Health Organization (WHO). (The Times of India, Economic Times)

Variant Characteristics

NB.1.8.1 is characterized by specific spike protein mutations, including A435S, V445H, and T478I. These mutations may contribute to increased transmissibility and potential immune evasion. However, current evidence suggests that the variant does not cause more severe illness compared to previous strains. (ap7am.com, The Times of India, Continental Hospitals)

Symptoms

Reported symptoms associated with NB.1.8.1 are similar to those of other Omicron variants and include:

• Sore throat
• Fatigue
• Mild cough
• Fever
• Muscle aches
• Congestion
• Headaches
• Nausea
• Loss of appetite
• Gastrointestinal issues (Economic Times, The Times of India)

Some cases have also reported persistent low-grade hyperthermia, a mild elevation in body temperature. (Economic Times)

Public Health Response

World Health Organization (WHO)

The WHO has designated NB.1.8.1 as a Variant Under Monitoring (VUM). Their preliminary risk assessment indicates a low global public health risk, and current COVID-19 vaccines are expected to remain effective against this variant. (The Times of India, Avian Flu Diary)

Preventive Measures

Health authorities recommend continued adherence to preventive measures:

• Wearing masks in crowded places
• Maintaining good hand hygiene
• Staying up to date with COVID-19 vaccinations and boosters (Economic Times, The Times of India)

Individuals experiencing symptoms are advised to seek testing and medical consultation promptly. (The Times of India)